TY -的T1神经并发症Osler-Weber-Rendu综合症:病例报告和文献综述(P3.058) JF -神经学乔-神经学六世- 84 - 14补充SP - P3.058盟萨尔曼·Farooq盟Ashkan Mowla AU -艾哈迈迪A首页bdelRazek盟Azher Iqbal AU -罗伯特·索耶Y1 - 2015/04/06 UR - //www.ez-admanager.com/content/84/14_Supplement/P3.058.abstract N2 -目的:防止Osler-Weber-Rendu综合症的神经系统并发症(OWRS),也被称为遗传性出血性毛细血管扩张,通过早期诊断和适当的治疗。背景:OWRS是一种罕见的遗传性疾病,其特征是毛细管扩张和过度出血。脑脓肿和缺血性中风是罕见但潜在的严重并发症,引起的反常栓塞肺动静脉畸形(avm)。设计/方法:我们描述一个56岁的女人,过去病史的OWRS向应急部门怀疑中风。核磁共振成像显示脑脓肿接受抗生素治疗。肺血管造影显示recanalized动静脉畸形的左叶肺栓塞15年前。结果:血管内栓塞是为了避免未来神经并发症和常规随访显示动静脉栓塞等并发症的预防血管再通的过程。结论:脑脓肿或缺血性中风必须预期OWRS史患者出现神经系统症状。这类病人的家属应该筛查OWRS与适当的基因测试。OWRS患者,无论是否有症状,应筛选肺动静脉。 If found, pulmonary AVM’s should be treated to prevent paradoxical embolism which can result in brain abscess or ischemic stroke, both of which can be potentially fatal. Endovascular embolization is the treatment of choice for pulmonary AVMS and a long term follow-up is recommended after the procedure to prevent any complications. Those patients treated for pulmonary AVMs, likely should be screened for recanalization with a pulmonary angiogram at routine intervals, suggested to be every 10 years. Our case illustrates that CT angiogram can be insufficient for this task. Study Supported by: SelfDisclosure: Dr. Farooq has nothing to disclose. Dr. Mowla has nothing to disclose. Dr. AbdelRazek has nothing to disclose. Dr. Iqbal has nothing to disclose. Dr. Sawyer has nothing to disclose.Tuesday, April 21 2015, 2:00 pm-6:30 pm ER -