RT期刊文章SR电子T1栓塞中风与自发的血管再通(P3.085)摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯SP P3.085 VO 84 14补充A1首页 Sourabh Lahoti A1 Sankalp Gokhale A1路易Caplan A1的帕特里克•米歇尔A1 Yves参孙A1夏洛特罗索A1 Kaustubh Limaye A1医生Hinduja A1 Aneesh Singhal A1赛义德·阿里·A1理查德Kryscio A1尼基塔Dedhia A1 Shirish Hastak A1大卫Liebeskind A1 L小矮星年2015 UL //www.ez-admanager.com/content/84/14_Supplement/P3.085.abstract AB目的研究是否与溶栓改善临床结果静脉溶栓栓塞中风病人有自发的血管再通。背景没有随机对照试验报告前血管成像获得的溶栓治疗。栓塞性中风患者的溶栓药物的影响没有明显的血管闭塞在演讲是未知的设计/方法回顾,观察八点多中心研究中心从美国、欧洲和印度。医疗记录的患者呈现在过去五年缺血性中风,没有成像(CTA / MRA)血管闭塞的证据进行了分析。患者分为两组,一个接受溶栓治疗和其他没有。根据大小和位置梗死的磁共振成像,患者被分成两个子组,栓子阻塞与自发的血管再通和腔隙中风。主要结果测量指标是良好的功能结果定义为改良Rankin规模< 2在3个月。结果栓塞性中风与自发的血管再通占共有154名患者,溶栓组49和105个非溶栓组。逻辑回归分析表明,患者接受溶栓治疗有更频繁的优秀成果优势比为4.90 (p < 0.01)。intra-cerebral出血症状更频繁的在溶栓组,但无统计学意义(6.1 (percnt)和1 (percnt) p = 0.09)。 Compared to cardioembolic subgroup of NINDS trial and intravenous thrombolysis arm of IMS 3, these patients had better response to thrombolytic therapy. Conclusions This study infers that thrombolysis remarkably improves clinical outcome in patients with embolic stroke who do not have visible arterial occlusion at presentation. A prospective study to validate these results is being planned.Disclosure: Dr. Lahoti has nothing to disclose. Dr. Gokhale has nothing to disclose. Dr. Caplan has received personal compensation in an editorial capacity for JAMA Neurology. Dr. Michel has received personal compensation for activities with Servier, Sanofi-Aventis Pharmaceuticals, and Boehringer Ingelheim Pharmaceuticals, as a speaker, steering committee member, and/or advisory board member. Dr. Samson has nothing to disclose. Dr. Rosso has nothing to disclose. Dr. Limaye has nothing to disclose. Dr. Hinduja has nothing to disclose. Dr. Singhal has received personal compensation for activities as a medicolegal expert witness. Dr. Singhal's spouse holds stock and/or stock options in Biogen Idec. Dr. Ali has nothing to disclose. Dr. Kryscio has nothing to disclose. Dr. Dedhia has nothing to disclose. Dr. Hastak has nothing to disclose. Dr. Liebeskind has received personal compensation for activities with Stryker and Covidien as a consultant. Dr. Pettigrew has nothing to disclose.Tuesday, April 21 2015, 2:00 pm-6:30 pm