% 0期刊文章%米格尔桑托斯%一个Ignacio Illan-Gala %会Vinceti %玛丽亚·路易萨%蜂蜜哈伯德%的铜质把手扎卡里·米勒%一个吉尔Rabinovici %布鲁斯·米勒%玛丽亚Gorno Tempini % T神经动作识别和对象的相关知识在神经退行性疾病(P6.196) % D J神经病学2015% % P P6.196 % V 84% N % X 14补充目的:识别神经解剖学的相关基础不同组件相关的神经退行性疾病患者的识别和对象知识的行动。首页背景:虽然各种动作识别的研究涉及到大群中风患者已经出版,前面在神经退行性疾病患者缺乏前瞻性研究。我们报告最大的动作识别研究神经退行性疾病的患者。方法:58科目与各种神经退行性疾病症状进行了哑剧识别测试中,44个词对象匹配测试,和42对象匹配任务要求位置判断涉及相同的对象。Voxel-wise多元回归分析进行结构磁共振成像扫描来确定体素与性能。确定体素相关的手势表示组件哑剧识别,我们重新进行手势识别的分析测试位置把每个科目的分数判断和词对象匹配测试统计模型;从而有效地控制了每一个受试者的能力访问对象词形式和位置相关的知识。结果:哑剧识别性能测试相关的体素在双边额,中期/后颞叶和顶叶区域。字对象匹配:大型集群在左/中期前颞叶皮层。中间位置的判断:各种集群在双边后颞gryrus,角形脑回,右额下回,左中期/颞下叶和左角回脑脊髓。 Controlling for patients’ ability to access word forms and location knowledge revealed remaining clusters in left posterior middle temporal and left inferior parietal areas. CONCLUSIONS: Our results suggest that action recognition is supported by a distributed left lateralized functional network that exhibits dissociable roles. In particular, left mid-posterior temporal and inferior parietal areas seem critical for representation of the gestural component of action recognition while frontal inferior regions may support cognitive control requirements common to all 3 tests.Disclosure: Dr. santos has nothing to disclose. Dr. Illan-Gala has nothing to disclose. Dr. Vinceti has nothing to disclose. Dr. Mandelli has nothing to disclose. Dr. Hubbard has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Rabinovici has received personal compensation for activities with PCME/Rockpointe as a speaker. Dr. Rabinovici receives research support from the National Institutes of Health, Alzheimer's Association, John Douglas French Alzheimer's Foundation, Tau C Dr. Miller has received personal compensation in an editorial capacity for Cambridge University Press, Guilford Publications, Inc., and Neurocase. Dr. Gorno Tempini has nothing to disclose.Thursday, April 23 2015, 7:30 am-12:00 pm %U