@article {KhanP07.260作者= {Quratulain汗和罗伯特Wharen h·迪恩和罗纳德·雷蒙Sanjeet Grewal编写和尼尔Graff-Radford}, title ={腰椎穿刺开启压力和手术风险正烷烃(P07.260)},体积={80}={7}补充数量,页面= {P07.260——P07.260} ={2013},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:本研究的目的是评估如果LP开启压力是在一组引流并发症有关。首页背景:最常见的手术并发症分流手术,一是排水。如果医生能预测这些风险可能会采取措施降低风险。设计/方法:我们与特发性评价116个连续的患者通过图表回顾一组分流的梅奥诊所1/1/09 12/31/11在杰克逊维尔之间。我们记录了开启压力和分流手术后的并发症。结果:我们分流的118名患者,排除2因为他们分流的次要原因,9有头部受伤的历史被认为是不太可能与脑积水和被包括在内。平均f /期是18个月,和年龄75.6岁。41 \ %是女性。100 \ %步态困难,75 \ %尿困难和64 \ %记忆丧失。83年,70 \ % \ %步态控制尿液和44 \ %的记忆改善手术后。都有CT扫描2 - 4周后op评估/排水。 37/116 (32\%) had over drainage on CT and 7 did not resolve with shunt valve pressure adjustment. The LP opening pressure (OP) was recorded in 105 patients and the median was 161 mm H2O. 14/53 (26\%) below the median and 20/52 (38\%) above the median had CT evidence of over drainage and all but 7 responded to shunt pressure adjustment. Interestingly, all 7 cases that did not respond were above the median.CONCLUSIONS: This study suggests that NPH patients undergoing shunt surgery with higher LP opening pressure above 161mm H2O may be at greater risk of over drainage complications. We caution that this is a small study and should be replicated. However if replicated surgeons may be able to decrease over drainage complications by setting the shunt valve opening pressure higher in those with higher LP opening pressures.Disclosure: Dr. Khan has nothing to disclose. Dr. Wharen has nothing to disclose. Dr. Deen has nothing to disclose. Dr. Reimer has nothing to disclose. Dr. Grewal has nothing to disclose. Dr. Graff-Radford has received personal compensation for activities with Codman. Dr. Graff-Radford has received personal compensation in an editorial capacity for the Neurologist. Dr. Graff-Radford has received research support from Janssen, Pfizer Pharmaceuticals, Medivation, Forrest, and Allon.Thursday, March 21 2013, 2:00 pm-7:00 pm}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/80/7_Supplement/P07.260}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }