% 0期刊文章% Rodolfo Savica %一个詹姆斯·鲍尔布兰登Grossardt % %布拉德利Boeve %沃尔特·罗卡J . Ahlskog % % T路易体痴呆和帕金森症和痴呆的发病率(P03.097) % D J神经病学2013% % P P03.097-P03.097 % V 80% N % X 7补充目的:探讨od和路易体痴呆发病率(下文)在奥姆斯特德县的居民,MN和比较它ot帕金森症的发病率与痴呆(P首页DD)。背景:我们研究了路易体痴呆的发病率(下文)在奥姆斯特德县的居民,MN,与老年痴呆症和帕金森症的发病率相比(PDD)。设计/方法:我们使用的医疗records-linkage系统罗彻斯特流行病学项目识别所有发达帕金森症的人从1991年到2005年(15年)。运动障碍专家审查每个疑似病人的完整的医疗记录确认诊断。结果:在542事件帕金森症的情况下,64年路易体痴呆46 PDD。下文的发生率为3.5每100000人每年总的来说,随着年龄的增长而急剧增加。同样,PDD的发病率是2.5总体而言,随着年龄的增长也急剧增加。路易体痴呆的发生率PDD是5.9。下文是年轻患者在出现症状和有更多比PDD患者记录的幻觉和认知的波动。男人比女人有更高的发病率下文在年龄谱。男人与女人的区别在下文的风险比的差异更极端的帕金森氏症的风险,正如之前报道的相同的人口。特别是,我们观察到的发病率男性下文4.8和2.2与18.7相比,女性在男性和女性的10.2 PD。临床诊断的病理符合24 31病人尸检(77.4%)。结论:下文的总体发病率低于率为帕金森病。 DLB risk not only increases steeply with age, but is markedly greater in men. The men to women difference may suggest different biologic mechanisms.Supported by: Mayo Foundation for Medical Education and Research. In addition, data were obtained from the Rochester Epidemiology Project, which is supported by the National Institute on Aging of the National Institutes of Health under Award Number R01AG034676.Disclosure: Dr. Savica has nothing to disclose. Dr. Grossardt has nothing to disclose. Dr. Bower has received personal compensation for activities with Teva Neuroscience and Merck & Co., Inc. Dr. Boeve has received research support from Cephalon, Inc.; Allon Therapeutics; and GE Healthcare. Dr. Ahlskog has nothing to disclose. Dr. Rocca has nothing to disclose.Tuesday, March 19 2013, 2:00 pm-6:30 pm %U