TY - T1的血管造影和血管内治疗急性缺血性中风后临床结果由于Vertebrobasilar遮挡:谢谢的汇集分析注册表,谢谢,神经学和多谢谢试验(P06.215) JF -乔-神经病学SP - P06.215 LP - P06.215六世- 78 - 1补充非盟-劳尔Nogueira盟都铎Jovin AU -韦德史密斯AU -玛丽莲Rymer AU -大卫Liebeskind AU -罗纳德·Budzik AU -托马斯·德夫林AU -加首页里·沃克AU -希勒米Lutsep Y1 - 2012/04/26 UR - //www.ez-admanager.com/content/78/1_Supplement/P06.215.abstract N2 -目的:描述血管内血栓切除术的结果在一个大型前瞻性群组急性基底动脉闭塞(包)的病人。背景包是一个严重的但不常见的条件仅占6% -10%的大船中风。设计/方法:我们的群组包括所有保病人从三个不同的潜在血栓切除术研究——谢谢审判,审判多谢谢,谢谢注册表。成功再通被定义为TIMI 2 - 3谢谢/脑缺血试验和TICI谢谢注册表2 - 3。好的结果被定义为90天的夫人≤2。结果:确定了九十九名患者(平均年龄61.6±15年(范围、31 - 93);男性性别,70.7%;意味着基线署,20.5±9.4(中位数,19);基线mRS0-1, 95.9%)。14例患者(14.1%)接受pre-procedure IV rt-PA。均值time-from-symptom-onset (TSO)动脉穿刺是9.23±12.45小时(平均6.15),34.1%的患者在8小时。所有患者接受至少一个通过的谢谢(平均2.3±1.6)。其他治疗方法包括:动脉内的rt-PA /尿激酶(53.5%),近端血管成形术(22.1%,19/86)或支架(14.0%,12/86),半影(15.3%,11/72)和其他机械(29.1%,25/86)。成功再通达到88.9% (88/99)。The overall mean/median NIHSS dropped from 20.5±9.4/19 on admission to 13.4±14.5/6 on discharge.The overall rate of good outcomes was 31.6%(31/98). 90-day mortality was 38.8%(38/98). The SICH rate was 8.9%(7/79). The rate of good outcome was numerically higher (34.5% vs.9.1%) and mortality was numerically lower (36.8% vs.54.5%) in the revascularized versus non-revascularized patients. Notably, only one of 31(3.2%) patients achieved a good outcome in the absence of recanalization.Patients with good outcome had significantly lower age (56.6 vs.63.6), baseline NIHSS (14.86 vs.23.15),and hypertension (51.6% vs.73.1%) but higher baseline functional status (mRS 0-1, 100% vs.93.8%) as compared to patients with bad outcomes. However, there was no difference in terms of TSO to puncture(9±13 vs.9±13 hours),glucose levels(130±27 vs.152±62mg/gL),intubation(82.6% vs.90.4%), or treatment modalities between these two groups.Conclusions: Mechanical thrombectomy in BAO appears to be associated higher recanalization rates than previous reports of intravenous or intra-arterial thrombolysis. In concordance to previous studies, the chances of good outcomes are dismal in the absence of recanalization.Supported by: Concentric Mecical, Inc.Disclosure: Dr. Nogueira has received personal compensation for activities with Concentric Medical, Inc., ev3 Neurovascular, Inc., Coaxia, Inc., and Rapid Medical, Inc. Dr. Jovin has received personal compensation for activities with Covidien-eV3, Concentric Medical Inc, Stryker, and NIT as a consultant. Dr. Jovin has received personal compensation in an editorial capacity for Journal of Neuroimaging. Dr. Smith has received personal compensation for activities with Cocentric Medical, Inc., as a consultant. Dr. Smith holds stock and/or stock options in Cocentric Medical, Inc. Dr. Rymer has received personal compensation for activities wtih Concentric Medical and Genentech Inc. as a speaker. Dr. Liebeskind has received personal compensation for activities with Concentric Medical, Inc. and CoAxia, Inc. as a consultant. Dr. Budzik has received personal compensation for activities with Concentric Medical, Inc. Dr. Devlin has received personal compensation for activities with Concentric Medical, Inc. as a consultant. Dr. Walker has received personal compensation for activities with Concentric Medical, Inc as an employee. Dr. Lutsep has received personal compensation for activities with Gore.Thursday, April 26 2012, 07:30 am-12:00 pm ER -