PT -期刊文章盟Solene Ronsin盟-蒋禄卡Deiana AU - Ana Filipa Geraldo盟-弗朗索瓦丝Durand-Dubief AU -罗兰Thomas-Maisonneuve盟Maite Formaglio盟小薇吉妮Desestret AU -大卫Meyronet盟诺伯特•Nighoghossian AU - Yves Berthezene盟杰罗姆Honnorat AU -弗朗索瓦Ducray TI - Pseudotumoral表示脑淀粉样蛋白- 10.1212 / WNL angiopathy-related炎症援助。0000000000002444 DP - 2016年3月08年TA -神经病首页学第六PG - 912 - 919 - 86 IP - 10 4099 - //www.ez-admanager.com/content/86/10/912.short 4100 - //www.ez-admanager.com/content/86/10/912.full所以Neurology2016 08年3月;86 AB -目的:识别的临床和放射特性应该提高pseudotumoral表示怀疑的脑淀粉样angiopathy-related炎症(CAA-I)。方法:我们回顾了5个新诊断的特点和23之前报道CAA-I成像结果的病人最初解释为中枢神经系统肿瘤。结果:大多数情况下(85%)发生在病人在60岁。演讲的临床特征包括亚急性认知能力下降(50%),混乱(32%)、焦赤字(32%),癫痫发作(25%)、头痛(21%)。大脑MRI显示渗透性的白质病变,表现出局部质量效应没有实质增强(93%)。总的来说,这些发现被解释为低级神经胶质瘤或淋巴瘤。18例患者(64%)接受了活组织检查,这是nondiagnostic 4例(14%),6例(21%)接受了手术切除。影像学表现的误解的主要原因是缺乏T2 *三梯度召回回波(T2 * gre)序列初始成像(89%)。随后表现(39%)时,T2 * gre序列显示多个特征皮层和皮层下microhemorrhages在所有情况下。灌注磁共振成像和磁共振光谱学(夫人),病人的一个子集上执行,表示相对脑血流量明显减少,一个正常的代谢率。Conclusion: The identification of one or several nonenhancing space-occupying lesions, especially in elderly patients presenting with cognitive impairment, should raise suspicion for the pseudotumoral presentation of CAA-I and lead to T2*-GRE sequences. Perfusion MRI and MRS appear to be useful techniques for the differential diagnosis of this entity.Aβ=β-amyloid; CAA=cerebral amyloid angiopathy; CAA-I=CAA-related inflammation; DWI=diffusion-weighted imaging; FLAIR=fluid-attenuated inversion recovery; 1H-MRS=proton magnetic resonance spectroscopy; MRA=magnetic resonance angiography; MTT=mean transit time; rCBF=relative cerebral blood flow; rCBV=relative cerebral blood volume; SWI=susceptibility-weighted imaging; T2*-GRE=T2*-weighted gradient-recalled echo