@article {CamposP1.268作者= {Yesica坎波斯和塞巴斯蒂安·桑切斯和莫林Deprince马修Vibbert和杰奎琳《m . Kamran阿特和巴拉克酒吧和戴安娜Tzeng Lori希恩和假虎刺属皮和罗德尼·贝尔和Stavropoula Tjoumakaris帕斯卡Jabbour和罗伯特Rosenwasser弗雷德林康},title ={静脉注射组织纤溶酶原激活物的结果在同一年缺血性中风(P1.268)},体积={86}={16}补充数量,elocation-id = {P1.268} ={2016},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:研究结果在静脉注射组织纤溶酶原激活物(IV-tPA)与急性缺血性中风间。首页背景:数据显示八旬老人少有利post-IV-tPA-administration结果比年轻病人。方法:横断面研究分析2013 - 2015年从托马斯杰弗逊大学医院远程医疗中风病人数据网络。主要结果是贫穷的结果(长期护理或死亡)出院。二次结果是出血性转换。我们比较的结果八旬老人(病人80 - 89岁)与年轻患者。我们使用美国国立卫生研究院的中风尺度(署)录取(α)和放电(δ)署分数作为神经恶化和计算中位数不同的代理人(Δ-NIHSS)对使用Wilcoxon-Signed-Rank匹配测试。更高的署分数代表了更严重的症状。我们使用逻辑回归来确定预测的结果。结果:这项研究涉及了197名患者(平均年龄69 {\ textpm} 16年),包括52个八旬老人和104名妇女。 Median αNIHSS was 9 (Interquartile Range [IQR] 14) and median δNIHSS 6 (IQR 15). The IV-tPA-administration rate was similar among groups at 50[percnt]. The octogenarian group had a higher median αNIHSS (16, IQR 16 vs. 8, IQR 11, p<=0.01), more women (69[percnt] vs. 45[percnt], p.003), and a higher poor-outcome rate (61[percnt] vs. 23[percnt], p<=0.0001) than the younger group, but no in-hospital mortality (25[percnt] vs. 14[percnt], p=0.09). Younger patients had a higher median Δ-NIHSS than octogenarians (5 vs. 0, p.0.001). Adjusting for age, sex, IV-tPA, year, and physician, poor outcome predictors were octogenarian (OR 4.1; CI, 1.6-10.9, p.0.003) and αNIHSS\>9 (OR 8.7; CI, 3.7-22.7, p\<0.0001). We observed an interaction with poor outcome and IV-tPA for octogenarians (OR 1.9; CI, 1.2-3.1, p=0.007) only. All groups had similar cumulative hemorrhagic-conversion rates (3[percnt]). Conclusions: Older patients had a higher risk of poor outcome at hospital discharge and this effect was independent of hemorrhagic transformation or in-hospital neurological deterioration.Disclosure: Dr. Campos has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Deprince has nothing to disclose. Dr. Vibbert has nothing to disclose. Dr. Urtecho has nothing to disclose. Dr. Athar has nothing to disclose. Dr. Bar has nothing to disclose. Dr. Tzeng has nothing to disclose. Dr. Sheehan has nothing to disclose. Dr. Pineda has nothing to disclose. Dr. Bell has nothing to disclose. Dr. Tjoumakaris has nothing to disclose. Dr. Jabbour has nothing to disclose. Dr. Rosenwasser has nothing to disclose. Dr. Rincon has nothing to disclose.Saturday, April 16 2016, 8:30 am-7:00 pm}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/86/16_Supplement/P1.268}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }