在泰- T1的白质高密度急性HIV感染的胼胝体(P1.322) JF -神经学乔-神经学六世- 86 - 16补充SP - P1.322盟Shaista阿拉姆AU -斯科特·明茨盟Lori希恩Y1 - 2016/首页04/05 UR - //www.ez-admanager.com/content/86/16_Supplement/P1.322.abstract N2 -简介:在胼胝体白质hyperintensities看到(CC)可以有一个广泛的差异。它包括脱髓鞘疾病,肿瘤,梗死灶。CC的可逆损伤已被证明发生在病毒性脑炎。其他疾病如癫痫和艾滋病相关的痴呆可以导致CC瞬态信号异常。在这里,我们提出一个案件的T2 hyperintensity CC的压部设置的急性感染艾滋病毒。方法/结果:一位32岁的同性恋男子恢复槌状脚趾手术发达右手麻木和无力躺在床上。在15分钟内蔓延到他的右臂麻木和弱点,然后他的左臂。他还注意到双边腿无力,吞咽困难。症状完全解决在6到8个小时。类似症状再次出现第二天在35分钟内恶化,几乎完全瘫痪。他们在八到十二个小时解决。 Three months prior he had tested negative for HIV-1 infection as part of routine screening for sexually transmitted infections. Following the development of symptoms, CSF was unremarkable, and MRI of the brain with contrast showed T2 hyperintensities in the splenium of the CC. A repeat MRI done 2 months later remained unchanged. On repeat testing he was positive for HIV-1. Conclusion: Patients may have neuroradiologic findings related to HIV even before seroconversion occurs. Acute HIV infection should be in the differential of a patient with T2 hyperintensities as seen in the CC. Consider PCR testing in patients with high clinical suspicion for HIV if no antibody is detected.Disclosure: Dr. Alam has nothing to disclose. Dr. Mintzer has received personal compensation for activities with UCB Pharma, Sunovion, Upsher-Smith Laboratories, Pfizer Inc., SK Pharmaceuticals, Vertex Pharmaceuticals, and Eisai Inc. as a speaker and/or consultant. Dr. Sheehan has nothing to disclose.Saturday, April 16 2016, 8:30 am-7:00 pm ER -