% 0期刊文章% Luca Massacesi % T Perivenular分布评估白质病变的MRI可以区分从炎性病变女士小血管疾病(P6.121) % D J神经病学2016% % P P6.121 X % V % 86% N 16补充目的:验证大脑白质(WM) Perivenular病变(PVL)作为标记的MS诊断背景:核磁共振是一个敏感的工具,用于检测脑白质病变(WM),但其特异首页性较低。多发性硬化(MS)病变发展沿着中央静脉成像PVL可以区分其他疾病相关的WM病变系统性自身免疫性疾病(悲伤而已),炎症的大脑小血管疾病方法:女士和悲伤在MRI大脑参与包括和接收一个在1.5 t磁共振成像扫描。体积T2 * epi + Gd和天赋序列。PVL被定义为hyperintense信号完全围绕intralesional hypointense信号中至少2垂直的平面。结果:17和14女士伤心了。便悄然包括5遗传病综合症(BS), 4系统性红斑狼疮(SLE)和5 Antiphospholipid综合征(APS)。)便悄然的多数(12/14)完成麦当劳MRI在空间传播的标准。数量和体积的病变相似女士和伤心。中位数[percnt] PVLs频率是89 (min-max, 68 - 100)组和女士15 (min-max 0-50;悲伤组p < 0.0001)。 BDs presented the highest PV[percnt] among SAD patients (median = 40, min-max 16-50; p= 0.02). The difference between the groups in cases with < 50[percnt] PVL was higly significant (p < 0.001, Fisher exact test). Sensitivity and specificity of the method resulted of 100[percnt]. Conclusions: The frequency of PVL is higher in MS than in SAD involving the CNS with no overlap, indicating that it can be efficiently evaluated by MRI even at low field strength and that it could also be used in differential diagnosis among MS and other CNS disorders.Disclosure: Dr. Massacesi has nothing to disclose.Thursday, April 21 2016, 8:30 am-5:30 pm %U