文摘
摘要目的:开发前期临床评分系统预测差post-endovascular血栓切除术(EVT)结果在急性中风分流过程中。
背景:徒劳的血管再通后(FR)是一个不利的结果成功EVT急性缺血性中风患者。目前还没有临床评分系统,可以准确地预测FR。
设计/方法:连续EVT患者前循环大血管闭塞中风被确定在综合中风中心从2016年到2021年,和临床信息记录。FR是定义为一个90天的改良Rankin 4或更高的规模(夫人)尽管实现修改在脑梗死溶栓(mTICI)得分2 b或更高。多变量回归分析用来确定FR的独立危险因素,和一个评分系统构造。
结果:鉴定了619个病人,483例成功再通和可用的90天的随访数据进行了分析。总的来说,FR是观察到46.5%的患者。从随机选择培训组(n = 357),个人FR的风险因素识别和用于构造带10分得分:基线残疾(1点:基线≥2)夫人,年龄(1点:60 - 69年,2点:70 - 79年,3点:80 - 84年,4分:85岁以上),署(2分:- 3分:在18到22岁,和4分:23或更高),和延迟最后正常(1点:≥6小时)。乐队得分取得了良好的可预测性FR的接受者操作特征曲线下面积0.80在我们培训组和0.78在我们验证队列。总数的88.2%和90.2%的患者,80岁或更老的乐队≥7有90天的夫人4或更高,尽管成功的EVT血管再通。
结论:乐队的分数是一个简单的临床评分系统预测的FR,它有可能作为一种有价值的诊断工具,医生在实际设置。
披露:陈先生已经收到了来自国家健康性的研究支持。Colasurdo博士没有披露。菲普斯博士没有披露。米勒博士的机构收到美敦力公司的研究支持。米勒博士的机构收到Cerenovus研究支持,DePuy辛迪思的产品,公司. .米勒博士的机构已经接到InSightec研究支持。米勒博士的机构已经接到Microvention研究支持。米勒博士的机构已经接到Microvention研究支持。米勒博士的机构已经接到InSightec研究支持。米勒博士的机构已经接到MicroVention研究支持。 The institution of Dr. Miller has received research support from InSightec. The institution of Dr. Miller has received research support from Vesalio. Jacob Cherian has nothing to disclose. Dr. Marino Granados has nothing to disclose. Dr. Cronin has nothing to disclose. Dr. Wozniak has nothing to disclose. Dheeraj Gandhi has nothing to disclose. Dr. Chaturvedi has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astra Zeneca. Dr. Chaturvedi has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for University of Calgary. Dr. Chaturvedi has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for American Heart Association. Dr. Chaturvedi has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Ramar & Paradiso. Dr. Chaturvedi has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Cole, Scott, Kissane. The institution of Dr. Chaturvedi has received research support from NINDS. Gaurav Jindal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Penumbra.
