文摘
摘要目的:比较结果的预测使用皮质阿尔伯塔中风程序早期的计算机断层扫描(方面)对总评分方面,大血管闭塞中风发生血栓切除术。
背景:10点方面占皮层下结构,更有可能梗塞和差别与长期的结果相比,受伤的皮层区域。更具体,cortically-weighted支持率方面得分可以更准确地预测长期成功的血管再通后功能的结果。
设计/方法:注册表2的数据全面中风中心(网站1:2016 - 2021;网站2:2019 - 2021)包括M1患者或颈内动脉(ICA)遮挡了血栓切除术合并进行分析。主要结果是90天的改良Rankin的转变(夫人),调整先验年龄,pre-stroke夫人,基线国立卫生研究院的中风尺度,M1和颈内动脉(ICA)闭塞,和成功再通(TICI 2 b / 3)。10点方面的培训模型(tASPECTS)与7 - point cortical-weighted方面(cASPECTS)生成在站点1和验证站点2中,使用接收器算子特征与模型相比(ROC)和纠正Akaike信息准则(AICc)。
结果:328包括病人(网站1 /培训组= 181;网站2 /验证= 147),平均年龄是71 y(差61.25—-82),其中119 (36.28%)ICA闭塞,与平均tASPECTS 9 (IQR 8 - 10)和中位数cASPECTS 6(差5 - 7)。在推导cASPECTS队列,多层次ROC曲线生成、调整与曲线下的区域(AUC)预测转变夫人从0.8546 - -0.9110 (AICc = 690.078, r ^ 2 = 0.5936)。在验证中,误分类率为71.6%,然而,当扩展的灵活性(+ /−1单元)夫人,模型分类验证网站数据正确的55.8%的时间。tASPECTS训练队列,夫人预测类的AUC范围从0.8812 - -0.9250 (AICc = 693.646, r ^ 2 = 0.6165),在模型表现的病例中没有区别cASPECTS (p = 0.14)。在验证中,误分类率为73.47%,提高到50.3%正确当扩展灵活性(+ /−1夫人单元)。
结论:cASPECTS和tASPECTS同样预测成功的血管再通后90天的夫人分数。
披露:Patel博士没有披露。Koneru女士没有披露。Penckofer女士没有披露。阮博士已经收到个人薪酬在500 - 4999美元的范围为在科学咨询服务或数据安全监测委员会Vesalio。阮博士已经收到个人补偿的范围0 - 499美元为科学顾问或服务数据安全监测委员会国家卫生研究院。阮博士已经收到个人薪酬在500 - 4999美元的范围为在科学咨询服务或数据安全监测委员会Avania。阮博士已经收到个人薪酬在500 - 4999美元的范围作为一个编辑,副主编、编辑顾问委员会成员啊哈。阮博士的机构已收到波士顿医疗中心的研究支持。阮博士的机构收到社会的研究支持的血管和神经学介入。首页Khalife博士没有披露。 Dr. Oliveira has nothing to disclose. Mohamad Abdalkader has nothing to disclose. Mr. Klein has nothing to disclose. Mr. Vigilante has nothing to disclose. Scott Kamen has nothing to disclose. Dr. Thomas has received personal compensation for serving as an employee of Cooper Univeristy Health Care. Dr. Thomas has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Stryker. Dr. Thomas has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medtronic. Dr. Thomas has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CereVasc. Dr. Siegler has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Ceribell. Dr. Siegler has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for AstraZeneca.
