文摘
摘要目的:种族/性别的影响进行评估,确定预测的结果在一群保血栓切除术治疗患者。
背景:急性基底动脉闭塞(包)导致高发病率和死亡率。最近来自中国的随机对照试验证明机械血栓切除术的临床受益。还需要进一步的研究来理解这些试验的结果的普遍性。
设计/方法:pc搜索业务是一个大型多中心回顾性注册连续急性八大容量包血栓切除术治疗中心在美国从2015年7月- 2021年12月。病人被包含在这个注册表,如果他们收到机械血栓切除术或动脉内的溶栓在24小时内的最后一次看到正常。注册包括基线特征的数据,预处理和一种数据,影像学和临床结果。良好的临床结果被定义为≤3夫人。多元逻辑回归模型来评估种族和性别差异,确定良好的临床结果的重要预测因子。
结果:pc搜索业务捕获的519例患者,444年完成了90天的平均年龄是65 Y,太太(SD 15),署的意思是17岁(差8-26)和PC-ASPECTS值是10 (IQR 8 - 10)。种族是白人(81%)、黑(16%)和亚洲(1.6%)。百分之三十九的患者是女性。良好的血管再通(≥TICI 2 b)在82%的病人(N = 425)。百分之四十五的患者达到≤3夫人与总死亡率的41.4%,90天。百分之五十四的患者在6小时。在多变量分析中,TICI评分(可信区间2.01 - 10.05或4.58;p = 0.00)和PC-ASPECTS(可信区间1.21 - 3.46或2.05;p = 0.01)是唯一的良好预测指标的结果。
结论:良好的血管再通和pre-procedural PC-ASPECT得分是好的结果的重要预测因子对急性基底动脉阻塞在这个注册表接受血栓切除术。种族和性别没有预测的结果。
披露:Mierzwa博士没有披露。扎伊迪博士没有披露。Aladamat博士没有披露。Gharaibeh博士没有披露。Afreen博士没有披露。萨米艾尔卡萨伯没有披露。纳尔逊博士没有披露。奥尔特加古铁雷斯博士已经收到个人薪酬在10000 - 49999美元的范围为stryker担任顾问。奥尔特加古铁雷斯博士已经收到个人薪酬在10000 - 49999美元的范围为美敦力公司担任顾问。奥尔特加古铁雷斯博士已经收到个人薪酬在5000 - 9999美元的范围为microvention担任顾问。 Dr. Ortega Gutierrez has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for SVIN. The institution of Dr. Ortega Gutierrez has received research support from stryker. The institution of Dr. Ortega Gutierrez has received research support from Siemens. The institution of Dr. Ortega Gutierrez has received research support from IschemiaView. The institution of Dr. Ortega Gutierrez has received research support from Medtronic. Mr. Vivanco-Suarez has nothing to disclose. Dr. Farooqui has nothing to disclose. Dr. Jadhav has nothing to disclose. Dr. Desai has nothing to disclose. Dr. Toth has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Dynamed. Dr. Toth has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Microvention. Dr. Toth has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Medtronic. Dr. Alrohimi has nothing to disclose. Dr. Nguyen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Vesalio. Dr. Nguyen has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for NIH. Dr. Nguyen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Avania. Dr. Nguyen has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AHA. The institution of Dr. Nguyen has received research support from Boston Medical Center. The institution of Dr. Nguyen has received research support from Society of Vascular and Interventional Neurology. Mr. Klein has nothing to disclose. Mohamad Abdalkader has nothing to disclose. Dr. Salahuddin has nothing to disclose. Dr. Pandey has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NIH and SVIN- Journal. Dr. Pandey has stock in FlexDex. Dr. Pandey has stock in NextGen. The institution of Dr. Pandey has received research support from NIH. The institution of Dr. Pandey has received research support from Focused ultrasound foundation. Dr. Pandey has received intellectual property interests from a discovery or technology relating to health care. Sravanthi Koduri has nothing to disclose. Nirav Vora has nothing to disclose. Dr. Jumaa has nothing to disclose.
