文摘
摘要目的:评估早期和晚期的影响时间窗口在一群保血栓切除术治疗患者。
背景:急性基底动脉闭塞(包)导致高发病率和死亡率。最近来自中国的随机对照试验证明机械血栓切除术的临床受益。
设计/方法:pc搜索业务是一个全国范围的回顾注册表连续急性保治疗血栓切除术与来自八大容量中心在美国从2015年7月- 2021年12月。病人被包含在这个注册表,如果他们收到机械血栓切除术或动脉内的溶栓在24小时内的最后一次看到正常。注册包括基线特征的数据,预处理和内部程序数据,影像学和临床结果。良好的临床结果被定义为≤3夫人。次被一分为二成早期(< 6小时)和后期(> 6小时)的时间窗口。多元逻辑回归模型来评估预测的结果。
结果:pc搜索业务登记了519名患者,479年记录结果在90天,意味着last-seen-normal groin-puncture时间是132分钟时间窗口和初末的765分钟时间窗的病人;虽然署(vs 16日17日p 0.057)、年龄(平均65.8 vs 67.4, p 0.175), PC-ASPECTS(平均10 vs 9 p值0.45),和door-groin穿刺时间(295分钟vs 389 p 0.28)两组没有差异。良好的血管再通(≥TICI 2 b)在82%的病人在早期的时间窗口和81.5%在时间窗口(p 0.45)。好的结果率(45.8 vs 41.8, p值0.41),西奇(7.1 vs 6.8 p 0.897)和死亡率(40.3 vs 43.4 p 0.869)军团之间的相似。
结论:在急性基底动脉闭塞患者的个人电脑方面得分,相似率可以达到良好的临床结果在早期和晚期的时间窗口。
披露:Aladamat博士没有披露。Mierzwa博士没有披露。扎伊迪博士没有披露。Gharaibeh博士没有披露。Afreen博士没有披露。萨米艾尔卡萨伯没有披露。纳尔逊博士没有披露。Farooqui博士没有披露。Vivanco-Suarez先生没有披露。Jadhav博士没有披露。 Dr. Desai has nothing to disclose. Dr. Toth has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Dynamed. Dr. Toth has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Microvention. Dr. Toth has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Medtronic. Dr. Alrohimi has nothing to disclose. Dr. Nguyen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Vesalio. Dr. Nguyen has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for NIH. Dr. Nguyen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Avania. Dr. Nguyen has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AHA. The institution of Dr. Nguyen has received research support from Boston Medical Center. The institution of Dr. Nguyen has received research support from Society of Vascular and Interventional Neurology. Mr. Klein has nothing to disclose. Mohamad Abdalkader has nothing to disclose. Dr. Pandey has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NIH and SVIN- Journal. Dr. Pandey has stock in FlexDex. Dr. Pandey has stock in NextGen. The institution of Dr. Pandey has received research support from NIH. The institution of Dr. Pandey has received research support from Focused ultrasound foundation. Dr. Pandey has received intellectual property interests from a discovery or technology relating to health care. Sravanthi Koduri has nothing to disclose. Nirav Vora has nothing to disclose. Vora Shivangi has nothing to disclose. Dr. Jumaa has nothing to disclose. Dr. Ortega Gutierrez has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for stryker. Dr. Ortega Gutierrez has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for medtronic. Dr. Ortega Gutierrez has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for microvention. Dr. Ortega Gutierrez has received personal compensation in the range of $0-$499 for serving as an officer or member of the Board of Directors for SVIN. The institution of Dr. Ortega Gutierrez has received research support from stryker. The institution of Dr. Ortega Gutierrez has received research support from Siemens. The institution of Dr. Ortega Gutierrez has received research support from IschemiaView. The institution of Dr. Ortega Gutierrez has received research support from Medtronic.
