文摘
摘要目的:昏迷的发病率和功能特征的大血管闭塞(LVO)中风。
背景:昏迷是一个反应迟钝的状态,其特征是受损的唤醒和意识。中风昏迷的流行病学和病理生理学的勘探。
设计/方法:个人面对LVO是从07/2018到12/2020确认的。昏迷被定义为一个反应迟钝的受损状态唤醒和意识,实施3署项目1的分数。
结果:28/638(4.4%)例LVO中风患者出现昏迷。年龄中位数为65 (IQR 48 - 78);57%是女性。署中位数为32 (IQR 29-34)。闭塞的位置包括基(10)、椎体(2),P1后大脑(2),颈内动脉(4)M1(6),和M2大脑中动脉(4)。在所有14前LVO患者,急性LVO是单方面的。这些14日6有急性或慢性中风的证据包括侧半球;1经验丰富的发作;1经验丰富的心脏骤停;和1的慢性闭塞侧ICA。总的来说,20/28的人死于入学。 Of those who died, 9 presented with anterior LVO and 11 with posterior LVO. Eight patients were treated with EVT. For those untreated, reasons included established infarct with ASPECTS <6 (11), delayed presentation (2), pre-stroke disability (3), and absence of intracranial proximal occlusion on repeat imaging (2).
结论:并不少见LVO中风患者出现昏迷,和65%的患者没有接受EVT延迟报告或大型梗塞,强调需要保持高度怀疑的心理指标。虽然通常认为由于后LVO,昏迷在我们群是从前LVO同样可能导致的。进一步的研究,这些患者可能阐明昏迷的病理生理学。努力提高早期诊断和治疗是至关重要的给贫穷的结果。
披露:杨医生没有披露。Awad博士没有披露。安德列夫博士没有披露。Bonkhoff博士已经收到个人薪酬在500 - 4999美元的范围作为一个编辑,副主编、编辑顾问委员会成员神经影像学临床(爱思唯尔)。Schirmer博士没有披露。詹姆斯d·Rabinov在辉瑞股票。Stapleton博士已经收到个人薪酬在500 - 4999美元的范围为在科学咨询服务或数据安全监测委员会海关循环。立即家人Singhal博士已收到生原体的个人作为一个雇员补偿。Singhal博士已经收到个人薪酬在5000 - 9999美元的范围作为一个法医学的公司的专家证人。Singhal博士接到NIH-NINDS研究支持。 Dr. Singhal has received publishing royalties from a publication relating to health care. Dr. Singhal has received publishing royalties from a publication relating to health care. Dr. Singhal has received personal compensation in the range of $500-$4,999 for serving as a Honorarium (Education) with Biogen. Dr. Rost has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Stroke - AHA/ASA Journal. The institution of Dr. Rost has received research support from NIH. Dr. Rost has received publishing royalties from a publication relating to health care. Aman Patel has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Penumbra. Aman Patel has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Microvention. Aman Patel has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Medtronic. The institution of Aman Patel has received research support from Siemens. Dr. Regenhardt has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Rapid Medical. Dr. Regenhardt has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Johnson and Bell Trial Lawyers. The institution of Dr. Regenhardt has received research support from National Institutes of Health. The institution of Dr. Regenhardt has received research support from Society of Vascular and Interventional Neurology. The institution of Dr. Regenhardt has received research support from Heitman Foundation.
