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2023年5月23日 ;100 (21) 金博宝手机版官网首页 开放获取

睡眠模式和急性中风的风险

结果INTERSTROKE国际病例对照研究

视图ORCID概要克里斯汀•艾琳Mc凯西,Salim Yusuf,视图ORCID概要康纳法官,阿尔贝托Alvarez-Iglesias,视图ORCID概要格雷姆·j .纸巾,Shahram Oveisgharan,视图ORCID概要Albertino Damasceno,赫勒克林根贝格球队,视图ORCID概要安妮卡工厂的,Alvaro Avezum,会长Patricio Lopez-Jaramillo,丹尼斯·泽维尔,Xingyu王,Sumathy Rangarajan周二,马丁·奥唐纳,对于INTERSTROKE
第一次出版2023年4月5日, DOI: https://doi.org/10.1212/WNL.0000000000207249
克里斯汀•艾琳Mc凯西
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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  • 克里斯汀艾琳Mc凯西ORCID纪录
Salim Yusuf
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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康纳法官
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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  • 康纳法官ORCID纪录
阿尔贝托Alvarez-Iglesias
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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格雷姆·j .纸巾
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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  • 格雷姆·j .纸巾ORCID纪录
Shahram Oveisgharan
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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Albertino Damasceno
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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  • ORCID记录Albertino Damasceno
赫勒克林根贝格球队
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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安妮卡工厂的
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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  • 安妮卡罗森格ORCID纪录
Alvaro Avezum
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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会长Patricio Lopez-Jaramillo
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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丹尼斯·泽维尔
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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Xingyu王
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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Sumathy Rangarajan周二
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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马丁·奥唐纳
的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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的药(C.E.M.C.,C.J.,A.A.-I., M.O.D.), University of Galway, Ireland; Department of Medicine (S.Y., S.R.), Population Health Research Institute, McMaster University and Hamilton Health Sciences, Ontario, Canada; School of Medicine and Pharmacology (G.J.H.), Faculty of Health and Medical Sciences, University of Western Australia, Perth; Department of Medicine (S.O.), Rush Alzheimer Disease Research Center in Chicago, IL; Faculty of Medicine (A.D.), Eduardo Mondlane University, Maputo, Mozambique; Department of Neurology (H.K.I.), Rigshospitalet, University of Copenhagen, Denmark; Department of Molecular and Clinical Medicine (A.R.), University of Gothenburg and Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Medicine (A.A.), International Research Center, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil; Department of Medicine (P.L.-J.), Instituto de Investigaciones MASIRA, Universidad de Santander, Bucaramanga, Colombia; Department of Medicine (D.X.), St John's Medical College and Research Institute, Bangalore, India; and Department of Medicine (X.W.), Beijing Hypertension League Institute, China.
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睡眠模式和急性中风的风险
结果INTERSTROKE国际病例对照研究
克里斯汀•艾琳Mc凯西,萨利姆优素福,康纳法官,阿尔贝托。Alvarez-Iglesias,格雷姆·J。纸巾,ShahramOveisgharan,AlbertinoDamasceno,赫勒克林根贝格球队,安妮卡工厂的,AlvaroAvezum,会长PatricioLopez-Jaramillo,丹尼斯泽维尔,Xingyu王,SumathyRangarajan周二,马丁奥唐纳,对于INTERSTROKE
首页 2023年5月, One hundred. (21) e2191-e2203; DOI:10.1212 / WNL.0000000000207249

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  • Odds of All Stroke, ICH, and Ischemic Stroke* *Conditional logistic regression adjusted for age, occupation, marital status, and mRS at baseline (primary model). OR presented on a log scale. ICH = intracranial hemorrhage; mRS = modified Rankin scale; OR = odds ratio.
    " data-icon-position="" data-hide-link-title="0">图1
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    图1 所有中风的几率,我和缺血性中风

    *条件逻辑回归调整年龄、职业、婚姻状况、和夫人在基线(主模型)。或在对数尺度。我=颅内出血;夫人=改良Rankin规模;或=比值比。

  • Odds of All Stroke for Poor or Fair Sleep Quality, Sleep-onset Latency, Waking More Than Once, and Napping Status Adjustment models are as follows: model 1: univariate (conditional); model 2: adjusted for occupation, age, marital status, and mRS at baseline (conditional); model 3: adjusted for occupation, age, marital status, mRS at baseline, alcohol consumption, smoking history, leisure physical activity, total AHEI score, waist-to-hip ratio, body mass index (kg/m2), depressive symptoms, and global stress (conditional); model 4: adjusted for occupation, age, marital status, mRS at baseline, alcohol consumption, smoking history, leisure physical activity, total AHEI score, waist-to-hip ratio, body mass index (kg/m2), depressive symptoms, global stress, a history of hypertension or adjusted BP >140/90 mm Hg at admission, a history of diabetes or hemoglobin A1c ≥6.5%, a history of atrial fibrillation/flutter, and a diagnosis of OSA (conditional). *For all panels (A–D), the reference level for each individual sleep parameter is displayed in brackets. AHEI = Alternative Healthy Eating Index; BP = blood pressure; mRS = modified Rankin scale; OR = odds ratio; OSA = obstructive sleep apnea.
    " data-icon-position="" data-hide-link-title="0">图2
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    图2 所有中风的几率或公平的睡眠质量差,影响延迟,不止一次醒来,打盹的地位

    调整模型如下:模型1:单变量(条件);模型2:调整的职业、年龄、婚姻状况、和夫人在基线(条件);模型3:调整的职业、年龄、婚姻状况、夫人在基线,饮酒、吸烟史、休闲体育活动,总AHEI得分,腰臀比,身体质量指数(公斤/米2)、抑郁症状和全球压力(条件);模式4:调整后的职业、年龄、婚姻状况、夫人在基线,饮酒、吸烟史、休闲体育活动,总AHEI得分,腰臀比,身体质量指数(公斤/米2),抑郁症状,全球压力、高血压史或调整BP > 140/90毫米汞柱在承认,历史的糖尿病或糖化血红蛋白≥6.5%,心房纤维性颤动的历史/颤振和诊断阻塞性睡眠呼吸暂停综合症(条件)。*对所有面板(模拟),参考水平为每个单独的睡眠参数显示在括号中。AHEI =替代健康饮食指数;英国石油(BP) =血压;夫人=改良Rankin规模;或=优势比;阻塞性睡眠呼吸暂停阻塞性睡眠呼吸暂停。

  • Odds of All Stroke for Snoring, Snorting, Breathing Cessation, and OSA Score Panels A–C demonstrate odds of all stroke for symptoms of, or uncertainty surrounding, snoring, snorting, or gasping and breathing cessation, respectively. Panel D demonstrates the odds of all stroke, ischemic stroke, and ICH with a potential OSA score of 2–3. Adjustment models are as follows: model 1: univariate (conditional); model 2: adjusted for occupation, age, marital status, and mRS at baseline (conditional); model 3: adjusted for occupation, age, marital status, mRS at baseline, alcohol consumption, smoking history, leisure physical activity, total AHEI score, waist-to-hip ratio, body mass index (kg/m2), depressive symptoms, and global stress (conditional); model 4: adjusted for occupation, age, marital status, mRS at baseline, alcohol consumption, smoking history, leisure physical activity, total AHEI score, waist-to-hip ratio, body mass index (kg/m2), depressive symptoms, global stress, a history of hypertension or adjusted BP >140/90 mm Hg at admission, a history of diabetes or hemoglobin A1c ≥6.5%, a history of atrial fibrillation/flutter, and a diagnosis of OSA (conditional). *For all panels (a-d), the reference level for each individual sleep parameter is displayed in brackets. AHEI = Alternative Healthy Eating Index; BP = blood pressure; ICH = intracerebral hemorrhage; mRS = modified Rankin scale; OR = odds ratio; OSA = obstructive sleep apnea.
    " data-icon-position="" data-hide-link-title="0">图3
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    图3 吸食所有中风的几率打鼾,呼吸停止,阻塞性睡眠呼吸暂停综合症的分数

    面板得了展示所有中风症状的几率,或不确定性,打鼾、吸食,分别或喘息和呼吸停止。面板D演示了所有中风的几率,缺血性中风,我与一个潜在的阻塞性睡眠呼吸暂停综合症2 - 3分的。调整模型如下:模型1:单变量(条件);模型2:调整的职业、年龄、婚姻状况、和夫人在基线(条件);模型3:调整的职业、年龄、婚姻状况、夫人在基线,饮酒、吸烟史、休闲体育活动,总AHEI得分,腰臀比,身体质量指数(公斤/米2)、抑郁症状和全球压力(条件);模式4:调整后的职业、年龄、婚姻状况、夫人在基线,饮酒、吸烟史、休闲体育活动,总AHEI得分,腰臀比,身体质量指数(公斤/米2),抑郁症状,全球压力、高血压史或调整BP > 140/90毫米汞柱在承认,历史的糖尿病或糖化血红蛋白≥6.5%,心房纤维性颤动的历史/颤振和诊断阻塞性睡眠呼吸暂停综合症(条件)。*对所有面板(模拟),参考水平为每个单独的睡眠参数显示在括号中。AHEI =替代健康饮食指数;英国石油(BP) =血压;我=脑内出血;夫人=改良Rankin规模;或=优势比;阻塞性睡眠呼吸暂停阻塞性睡眠呼吸暂停。

  • Sleep Disturbance Symptom Burden (A) Cumulative number of sleep disturbance symptoms in cases and controls, where sleep disturbance symptoms include the following: sleeping for <6 or >7 hours at night, SOL, waking more than once, napping for >1 hour, unplanned napping, and presence or uncertainty surrounding snorting, snorting or gasping, and breathing cessation or choking. (B) Odds of all stroke in sleep disturbance symptom number categories. OR presented on a log scale. Model 1 is univariate (conditional); model 2 adjusts for occupation, age, marital status, and mRS at baseline (conditional); model 3 adjusts for occupation, age, marital status, mRS at baseline, alcohol consumption, smoking history, leisure physical activity, total AHEI score, waist-to-hip ratio, body mass index (kg/m2), depressive symptoms, and global stress (conditional); model 4 adjusts for occupation, age, marital status, mRS at baseline, alcohol consumption, smoking history, leisure physical activity, total AHEI score, waist-to-hip ratio, body mass index (kg/m2), depressive symptoms, global stress, a history of hypertension or adjusted BP >140/90 mm Hg at admission, a history of diabetes or hemoglobin A1c ≥6.5%, a history of atrial fibrillation/flutter, and a diagnosis of OSA (conditional). AHEI = Alternative Healthy Eating Index; BP = blood pressure; mRS = modified Rankin scale; OR = odds ratio; OSA = obstructive sleep apnea; SOL = sleep-onset latency.
    " data-icon-position="" data-hide-link-title="0">图4
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    图4 睡眠障碍症状负担

    (A)累积睡眠障碍症状的病例数和控制,睡眠障碍症状包括以下的地方:睡眠时间< 6 >晚上7小时,索尔,不止一次,醒来> 1小时午睡,无计划的打盹,存在或不确定性吸食,吸食或喘气,呼吸停止或窒息。(B)的中风几率睡眠障碍症状类别数量。或在对数尺度。模型1是单变量(条件);模型2调整职业、年龄、婚姻状况、和夫人在基线(条件);模型3调整职业、年龄、婚姻状况、夫人在基线,饮酒、吸烟史、休闲体育活动,总AHEI得分,腰臀比,身体质量指数(公斤/米2)、抑郁症状和全球压力(条件);模型4调整职业、年龄、婚姻状况、夫人在基线,饮酒、吸烟史、休闲体育活动,总AHEI得分,腰臀比,身体质量指数(公斤/米2),抑郁症状,全球压力、高血压史或调整BP > 140/90毫米汞柱在承认,历史的糖尿病或糖化血红蛋白≥6.5%,心房纤维性颤动的历史/颤振和诊断阻塞性睡眠呼吸暂停综合症(条件)。AHEI =替代健康饮食指数;英国石油(BP) =血压;夫人=改良Rankin规模;或=优势比;阻塞性睡眠呼吸暂停综合症=阻塞性睡眠呼吸暂停;索尔=影响延迟。

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