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2023年1月17日 ;100 (3) 金博宝手机版官网首页 开放获取

区分多发性硬化症从视AQP4-Neuromyelitis谱系障碍和MOG-Antibody疾病成像

罗莎Cortese,视图ORCID概要弗兰普拉多卡拉斯科,视图ORCID概要卡门病重,视图ORCID概要Alessia比安奇,华莱士Brownlee,视图ORCID概要Floriana De旧金山,伊莎贝尔·德·拉巴斯,视图ORCID概要弗朗西斯科·Grussu,视图ORCID概要卢卡斯海德尔,阿奴雅各,巴里斯Kanber,丽丝Magnollay,视图ORCID概要理查德·s·尼古拉斯,Anand旅行,腻过Yiannakas,视图ORCID概要艾哈迈德·t·Toosy,雅艾尔Hacohen,视图ORCID概要弗雷德里克Barkhof,奥尔加Ciccarelli
第一次出版2022年10月3日, DOI: https://doi.org/10.1212/WNL.0000000000201465
罗莎Cortese
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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弗兰普拉多卡拉斯科
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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卡门病重
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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  • 卡门病重ORCID纪录
Alessia比安奇
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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华莱士Brownlee
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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Floriana De旧金山
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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伊莎贝尔·德·拉巴斯
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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弗朗西斯科·Grussu
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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  • 弗朗西斯科·Grussu ORCID纪录
卢卡斯海德尔
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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阿奴雅各
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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巴里斯Kanber
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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丽丝Magnollay
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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理查德·s·尼古拉斯
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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  • 理查德·s . Nicholas ORCID纪录
Anand旅行
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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腻过Yiannakas
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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艾哈迈德·t·Toosy
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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  • 艾哈迈德·t·Toosy ORCID纪录
雅艾尔Hacohen
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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弗雷德里克Barkhof
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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  • 弗雷德里克Barkhof ORCID纪录
奥尔加Ciccarelli
的神经炎症(司令部,F.P.C.,比较温度,学士,b,F.D.A., I.D.L.P., F.G., L.H., L.M., A.T., M.Y., A.T.T., Y.H.R.C.P.C.H., F.B., O.C.), Queen Square MS Centre, UCL Queen Square Institute of Neurology, Faculty of Brain Science, University College of London; Department of Medicine (R.C.), Surgery and Neuroscience, University of Siena, Italy; Department of Medical Physics and Biomedical Engineering (F.P.C., B.K., F.B.), Centre for Medical Imaging Computing, University College of London; Universitat Oberta de Catalunya (F.P.C.), Barcelona, Spain; MS Centre of Catalonia (Cemcat) (C.T.), Vall d’Hebron Institute of Research, Spain; Radiomics Group (F.G.), Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Barcelona, Spain; Department of Biomedical Imaging and Image Guided Therapy (L.H.), Medical University of Vienna, Austria; NMO Clinical Service at the Walton Centre (A.J.), Liverpool, United Kingdom; Division of Multiple Sclerosis and Autoimmune Neurology (A.J.), Neurological Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates; Division of Brain Sciences (R.S.N.), Department of Medicine, Imperial College London; National Institute for Health Research (NIHR) (A.T., F.B., O.C.), University College London Hospitals (UCLH), Biomedical Research Centre; and Department of Radiology and Nuclear Medicine (F.B.), Amsterdam University Medical Centre, the Netherlands.
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区分多发性硬化症从视AQP4-Neuromyelitis谱系障碍和MOG-Antibody疾病成像
罗莎Cortese,弗兰普拉多博物馆卡拉斯科,卡门病重,Alessia比安奇,华莱士Brownlee,FlorianaDe旧金山,伊莎贝尔拉巴斯德,弗朗西斯科Grussu,卢卡斯海德尔,阿奴雅各,巴里斯Kanber,丽丝Magnollay,理查德·S。尼古拉斯,阿南德旅行,腻过Yiannakas,艾哈迈德·T。Toosy,雅艾尔Hacohen,弗雷德里克Barkhof,奥尔加Ciccarelli
首页 2023年1月, One hundred. (3) e308-e323; DOI:10.1212 / WNL.0000000000201465

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  • Differences in Brain and Cervical Cord Measures Between RRMS, AQP4-NMOSD, MOGAD, and Healthy Controls The boxplots show a lower number and volume of lesions and a higher degree of atrophy in patients with RRMS than patients with AQP4-NMOSD and MOGAD and healthy controls. AQP4-NMOSD = aquaporin-4 antibody–positive neuromyelitis optica spectrum disorder; MOGAD = myelin oligodendrocyte glycoprotein antibody–associated disease; RRMS = relapsing-remitting multiple sclerosis.
    " data-icon-position="" data-hide-link-title="0">图1
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    图1 名RRMS之间的差异在大脑和颈绳措施,AQP4-NMOSD, MOGAD和健康对照组

    箱线图显示较低的数量和体积损伤和名RRMS患者的萎缩程度高于AQP4-NMOSD和MOGAD患者和健康对照组。视AQP4-NMOSD = aquaporin-4抗体阳性neuromyelitis谱系障碍;MOGAD =髓少突细胞糖蛋白antibody-associated疾病;名RRMS =复发缓和多发性硬化。

  • Examples of Cortical Lesions Seen on Phase-Sensitive Inversion Recovery (PSIR) Images and Lesions With and Without the Central Vein Sign (CVS) on Susceptibility-Weighted Imaging (SWI) in RRMS, AQP4-NMOSD, and MOGAD In the upper figures, PSIR imaging showing lesions located exclusively in the cortex (intracortical, red arrow) or within the cortex and adjacent juxtacortical white matter (leukocortical, blue arrow) in RRMS, AQP4-NMOSD, and MOGAD. Intracortical and leukocortical lesions were detected in patients with RRMS (A), whereas 1 leukocortical lesion in 1 patient with AQP4-NMOSD (B) and 1 intracortical lesion in 1 patient with MOGAD (C) were found. In the lower figures, T2 and corresponding SWI of deep white matter lesions with (red arrow) or without (blue arrow) CVS in RRMS and AQP4-NMOSD. The dark vein was located centrally in a lesion in an RRMS patient (D), while it was absent in three lesions in an AQP4-NMOSD patient (E). AQP4-NMOSD = aquaporin-4 antibody–positive neuromyelitis optica spectrum disorder; MOGAD = myelin oligodendrocyte glycoprotein antibody–associated disease; RRMS = relapsing-remitting multiple sclerosis.
    " data-icon-position="" data-hide-link-title="0">图2
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    图2 皮质病变的例子出现在相敏反转恢复(PSIR)图像和中央静脉病变有或没有签署(CVS)在名RRMS Susceptibility-Weighted成像(瑞士),AQP4-NMOSD, MOGAD

    上数据,PSIR成像显示病变位于只在大脑皮层(皮层,红色箭头)或在相邻juxtacortical皮质和白质(leukocortical,蓝色箭头)名RRMS, AQP4-NMOSD, MOGAD。皮层和leukocortical病变发现名RRMS患者(A),而1 leukocortical病变1例患者AQP4-NMOSD (B)和1皮层病变1例患者MOGAD (C)被发现。下数据,T2和相应的瑞士深白质病变(红色箭头)或没有(蓝色箭头)CVS名RRMS AQP4-NMOSD。深静脉位于集中在一个名RRMS患者病变(D),虽然没有在三个病变AQP4-NMOSD病人(E)。AQP4-NMOSD = aquaporin-4抗体阳性neuromyelitis视谱系障碍;MOGAD =髓少突细胞糖蛋白antibody-associated疾病;名RRMS =复发缓和多发性硬化。

  • Central Vein Sign (CVS) Detected on Susceptibility-Weighted Imaging (SWI) in the Patient Groups The scatterplot shows the proportion of lesions with CVS (out of the total number of lesions) for each patient in the 3 diseases (orange = RRMS, green = AQP4-NMOSD, and blue = MOGAD). Patients without brain lesions are not displayed. Two of 8 patients with MOGAD were excluded from the rating (1 for poor SWI quality and 1 for extensive, confluent PD/T2 abnormalities). Note: 100% means that all lesions assessed showed the CVS. MOGAD = myelin oligodendrocyte glycoprotein antibody–associated disease; RRMS = relapsing-remitting multiple sclerosis.
    " data-icon-position="" data-hide-link-title="0">图3
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    图3 中央静脉标志(CVS)发现Susceptibility-Weighted成像(瑞士)患者组

    散点图显示病变的比例与CVS(病变)的总数3每个病人的疾病(橙色=名RRMS绿色= AQP4-NMOSD和蓝色= MOGAD)。而没有脑损伤病人是不显示。两个8 MOGAD患者被排除在评级(1为瑞士质量差和广泛,汇合的PD / T2异常)。注意:100%意味着所有病变评估显示,CVS。MOGAD =髓少突细胞糖蛋白antibody-associated疾病;名RRMS =复发缓和多发性硬化。

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