文摘
摘要目的:研究预测的结果在接受机械血栓切除术的患者急性中风。
背景:尽管与现代血栓切除术设备再通率高、功能独立只有实现约50%的病人。在这项研究中,我们旨在调查可怜的预测结果在病人机械血栓切除术成功再通。
设计/方法:一个多中心的国际数据库从9血栓切除术中心前瞻性收集。患者包括如果他们遇到前循环大血管闭塞(LVO)和接受机械血栓切除术(MT)成功再通。额外的标准是阿尔伯塔省中风项目早期CT扫描(方面)得分6,基线改良Rankin规模(夫人)0 - 2。主要结果是90天的夫人3 - 6。多元逻辑回归是用来识别预测的结果。
结果:共有1077名患者包括在这项研究中,528名(49%)不良结果(3 - 6)夫人在90天。良好的结果相比,穷人结果组年龄(年龄意味着±SD, 71±14 vs 65±14年;p < 0.001),有更高的入学署(平均数±标准差;18±6 vs 14±6;p = 0.001),得分较低的方面(中位数(差);8(3)和9 (2);p < 0.001)。对过程变量,修改组织脑梗死得分(mTICI) 2 c / 3是不太常见的贫困结果组(59%比67%;p = 0.006)。抗高血压药物的使用更频繁地在贫困结果组(60%比49%,p = 0.001)。症状性脑出血(西奇)更频繁的在贫穷的结果组(8%比0.6%; p<0.0001). In addition, acute kidney injury was more common in poor outcome group (13% vs. 7% p <0.001). On multivariate analysis, age, admission NIHSS, ASPECT score, sICH, AKI, antihypertensive use, and final mTICI score emerged as predictors of poor outcome.
结论:老年,更高的入学署,得分较低的方面,症状性脑出血,降压使用和mTICI 2 b与成功再通后的不良预后显著相关。
披露:Anadani博士没有披露。Orabi博士没有披露。Alawieh博士没有披露。Goyal博士没有披露。Pandhi博士没有披露。米切尔博士没有披露。Alexandrov博士已经收到个人赔偿咨询、担任科学顾问委员会说,基因泰克或其他活动,Cerevast医疗,西门子公司。迈尔博士没有披露。Psychogios博士已经收到个人赔偿咨询、担任科学顾问委员会说,与西门子Healthineers或其他活动。博士Psychogios收到西门子医疗解决方案的研究支持。 Dr. Inamullah has nothing to disclose. Dr. Rahman has nothing to disclose. Dr. Swisher has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Eisai and UCB. Dr. Keyrouz has nothing to disclose. Dr. Giles has nothing to disclose. Dr. Allen has nothing to disclose. Dr. Kansagra has nothing to disclose. Dr. Wolfe has nothing to disclose. Dr. Kan has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Consultant for Stryker and Medtronic. Dr. Kan holds stock and/or stock options in Inneuroco which sponsored research in which Dr. Kan was involved as an investigator. . Dr. Nascimento has nothing to disclose. Dr. Gory has nothing to disclose. Dr. De Marini has nothing to disclose. Dr. Spiotta has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Penumbra, Pulsar Vascular, Microvention, Stryker.
