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November 08, 2005; 65 (9) Clinical/Scientific Notes

Concurrent dolichoectasia of basilar and coronary arteries

Fernando Pico, Yves Biron, Marie Germaine Bousser, Pierre Amarenco
First published November 7, 2005, DOI: https://doi.org/10.1212/01.wnl.0000183285.80271.60
Fernando Pico
From the Department of Neurology (Dr. Pico), Versailles Mignot Hospital, Versailles, Department of Cardiology (Dr. Biron), Saint Laurent Clinic, Rennes, Department of Neurology and Stroke Centre (Dr. Bousser), Lariboisière University Hospital and Medical School, Paris, and Department of Neurology and Stroke Centre (Dr. Amarenco), Bichat University Hospital and Medical School, Paris, France.
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Yves Biron
From the Department of Neurology (Dr. Pico), Versailles Mignot Hospital, Versailles, Department of Cardiology (Dr. Biron), Saint Laurent Clinic, Rennes, Department of Neurology and Stroke Centre (Dr. Bousser), Lariboisière University Hospital and Medical School, Paris, and Department of Neurology and Stroke Centre (Dr. Amarenco), Bichat University Hospital and Medical School, Paris, France.
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Marie Germaine Bousser
From the Department of Neurology (Dr. Pico), Versailles Mignot Hospital, Versailles, Department of Cardiology (Dr. Biron), Saint Laurent Clinic, Rennes, Department of Neurology and Stroke Centre (Dr. Bousser), Lariboisière University Hospital and Medical School, Paris, and Department of Neurology and Stroke Centre (Dr. Amarenco), Bichat University Hospital and Medical School, Paris, France.
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Pierre Amarenco
From the Department of Neurology (Dr. Pico), Versailles Mignot Hospital, Versailles, Department of Cardiology (Dr. Biron), Saint Laurent Clinic, Rennes, Department of Neurology and Stroke Centre (Dr. Bousser), Lariboisière University Hospital and Medical School, Paris, and Department of Neurology and Stroke Centre (Dr. Amarenco), Bichat University Hospital and Medical School, Paris, France.
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Concurrent dolichoectasia of basilar and coronary arteries
Fernando Pico, Yves Biron, Marie Germaine Bousser, Pierre Amarenco
Neurology Nov 2005, 65 (9) 1503-1504; DOI: 10.1212/01.wnl.0000183285.80271.60

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Intracranial arterial dolichoectasia (IADE) is observed in 12% of patients with brain infarction. The artery most often affected is the basilar artery (BADE).1 Coronary artery ectasia (CAE) is the sacular or fusiform dilatation of coronary and is observed in 5% of coronary angiographies.2 CAE is associated with angina pectoris and myocardial infarction independently of coronary atherosclerosis.3 Both IADE and CAE have been reported in association with abdominal aortic aneurysm (AAA) in case series4 and case-control studies,5,6 suggesting that the process causing these arterial dilatations also affects other arterial beds. We previously found that IADE in stroke patients was strongly associated with a clinical history of myocardial infarction.1 There is no report of an association between IADE and CAE.

We report on four patients with BADE and CAE, one with AAA, suggesting that these abnormalities are part of a systemic vascular ectatic disease.

Case reports.

Patient 1.

A 73-year-old hypertensive, obese, diabetic man had unstable angina pectoris in 1985 with three vessels lesions treated by coronary artery bypass graft. In 1999, a follow-up coronary angiography showed no stenosis on the …

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Letters: Rapid online correspondence

  • Reply from the authors
    • Fernando Pico, Versailles Mignot Hospital, 177 rue de Versailles 78150 Le Chesnay Francef.pico@ch-versailles.fr
    • Pierre Amarenco, Paris France
    Submitted January 09, 2006
  • Concurrent dolichoectasia of basilar and coronary arteries
    • Ken Ikeda, Department of Neurology, PL Tokyo Health Care Center, Tokyo, Japan, 16-1, Kamiyamacho, Shibuyaku, Tokyo, 150-0047, Japankeni@pl-tokyo-kenkan.gr.jp
    • Hidetoshi Kashihara, Ken-ichi Hosozawa, Masaki Tamura, Shigeji Baba, Yasuo Iwasaki
    Submitted January 09, 2006
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