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September 11, 2012; 79 (11) Editorials

Autoimmune pain

An emerging concept

David L.H. Bennett, Angela Vincent
First published August 15, 2012, DOI: https://doi.org/10.1212/WNL.0b013e3182698dc3
David L.H. Bennett
From the Department of Neurorestoration (D.L.H.B.), Wolfson CARD, King's College London; and Neurosciences Group (A.V.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.
MB, PhD
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Angela Vincent
From the Department of Neurorestoration (D.L.H.B.), Wolfson CARD, King's College London; and Neurosciences Group (A.V.), Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.
FRS, FRCPath
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Autoimmune pain
An emerging concept
David L.H. Bennett, Angela Vincent
Neurology Sep 2012, 79 (11) 1080-1081; DOI: 10.1212/WNL.0b013e3182698dc3

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Autoantibodies to the voltage-gated potassium channel (VGKC) complex have been implicated in a number of autoimmune neurologic conditions, including limbic encephalitis, neuromyotonia, and Morvan syndrome (neuromyotonia, insomnia, and autonomic dysfunction).1,2 Although these antibodies are measured by radioimmunoprecipitation of brain tissue extracts labeled with 125I-α-dendrotoxin (a snake toxin that binds various …

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