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Sporadic inclusion body myositis (IBM) is distinguished from other inflammatory myopathies based on clinical and histopathologic features, including slowly progressive weakness in middle or later age, with a predilection for finger flexors, wrist flexors, and quadriceps muscles. We report 4 patients with IBM and chronic lymphocytic leukemia (CLL). Only one such patient has been reported previously.1
Footnotes
Author contributions: Dr. Greenberg: study concept and design. Dr. Beck: acquisition of data. Dr. Amato: critical revision of the manuscript for important intellectual content.
Study funding: No targeted funding reported.
Disclosure: E. Beck reports no disclosures relevant to the manuscript. A. Amato has served as a Consultant/Medical Advisory Board for Amgen, MedImmune, and Biogen Idec. S. Greenberg has received research support from the NIH, Muscular Dystrophy Association, MedImmune, LLC; has worked as a consultant for aTyr Pharma and at Scientific Advisory Board meetings for MedImmune, Biogen Idec, and Novartis; and has worked as an expert in litigation. Go to Neurology.org for full disclosures.
- Received October 20, 2013.
- Accepted in final form March 12, 2014.
- © 2014 American Academy of Neurology
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