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August 04, 2015; 85 (5) Contemporary Issues

A practical, simple, and useful method of categorizing interictal EEG features in children

Se Hee Kim, Christian M. Korff, Andrew J. Kim, Douglas R. Nordli
First published July 2, 2015, DOI: https://doi.org/10.1212/WNL.0000000000001805
Se Hee Kim
From the Department of Pediatrics (S.H.K., A.J.K., D.R.N.), Epilepsy Center, Ann & Robert H. Lurie Children's Hospital of Chicago, and the Northwestern University Feinberg School of Medicine, IL; and Pediatric Neurology (C.M.K.), Child and Adolescent Department, University Hospitals, Geneva, Switzerland.
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Christian M. Korff
From the Department of Pediatrics (S.H.K., A.J.K., D.R.N.), Epilepsy Center, Ann & Robert H. Lurie Children's Hospital of Chicago, and the Northwestern University Feinberg School of Medicine, IL; and Pediatric Neurology (C.M.K.), Child and Adolescent Department, University Hospitals, Geneva, Switzerland.
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Andrew J. Kim
From the Department of Pediatrics (S.H.K., A.J.K., D.R.N.), Epilepsy Center, Ann & Robert H. Lurie Children's Hospital of Chicago, and the Northwestern University Feinberg School of Medicine, IL; and Pediatric Neurology (C.M.K.), Child and Adolescent Department, University Hospitals, Geneva, Switzerland.
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Douglas R. Nordli Jr
From the Department of Pediatrics (S.H.K., A.J.K., D.R.N.), Epilepsy Center, Ann & Robert H. Lurie Children's Hospital of Chicago, and the Northwestern University Feinberg School of Medicine, IL; and Pediatric Neurology (C.M.K.), Child and Adolescent Department, University Hospitals, Geneva, Switzerland.
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A practical, simple, and useful method of categorizing interictal EEG features in children
Se Hee Kim, Christian M. Korff, Andrew J. Kim, Douglas R. Nordli
Neurology Aug 2015, 85 (5) 471-478; DOI: 10.1212/WNL.0000000000001805

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Abstract

We introduce a simple scheme of categorizing interictal EEG in patients with pediatric epilepsy. Five patterns of EEG can be determined by using 2 interictal EEG domains: organization of the background activity and a morphology/topography of epileptiform discharges. These patterns relate to commonly recognized categories of pediatric epilepsy: familial epilepsies, genetic generalized epilepsies, self-limited epilepsies, epilepsies with encephalopathy, and focal structural epilepsies. Each group has distinguishable clinical presentations, inheritance patterns, and outcomes. This categorization may be a useful educational tool; it may also guide decisions about further testing and management.

GLOSSARY

AED=
antiepileptic drug;
BCSSS=
benign childhood seizure susceptibility syndrome;
EIEE=
early infantile epileptic encephalopathy;
IED=
interictal epileptiform discharges

Footnotes

  • Go to Neurology.org for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

  • Received October 7, 2014.
  • Accepted in final form April 2, 2015.
  • © 2015 American Academy of Neurology
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Letters: Rapid online correspondence

  • Categorizing pediatric epilepsy by interictal EEG features
    • Nitin K. Sethi, Assistant Professor of Neurology, New York-Presbyterian Hospital, Weill Cornell Medical Center 525 East 68th Street, New York, NY 1006sethinitinmd@hotmail.com
    Submitted August 11, 2015
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  • Article
    • Abstract
    • GLOSSARY
    • CATEGORIZING EPILEPSY BY INTERICTAL EEG
    • A PILOT STUDY AT OUR CENTER
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    • DISCUSSION
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