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November 08, 2005 ; 65 (9) Clinical/Scientific Notes

Phosphorylated tau predicts rate of cognitive decline in MCI subjects: A comparative CSF study

K. Buerger,M. Ewers,N. Andreasen,R. Zinkowski,K. Ishiguro,E. Vanmechelen,S. J. Teipel,C. Graz,K. Blennow,H. Hampel
First publishedNovember 7, 2005, DOI: https://doi.org/10.1212/01.wnl.0000183284.92920.f2
K. Buerger
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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M. Ewers
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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N. Andreasen
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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R. Zinkowski
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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K. Ishiguro
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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E. Vanmechelen
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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S. J. Teipel
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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C. Graz
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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K. Blennow
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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H. Hampel
From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
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Full PDF
Citation
Phosphorylated tau predicts rate of cognitive decline in MCI subjects: A comparative CSF study
K.Buerger,M.Ewers,N.Andreasen,R.Zinkowski,K.Ishiguro,E.Vanmechelen,S. J.Teipel,C.Graz,K.Blennow,H.Hampel
首页 Nov 2005, 65 (9) 1502-1503; DOI:10.1212/01.wnl.0000183284.92920.f2

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Article Information

vol. 65 no. 9 1502-1503
DOI:
https://doi.org/10.1212/01.wnl.0000183284.92920.f2
PubMed:
16275849

Published By:
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN:
0028-3878
Online ISSN:
1526-632X
History:
  • First PublishedNovember 7, 2005.

Copyright & Usage:
© 2005

Author Disclosures

    1. K. Buerger, MD,
    2. M. Ewers, PhD,
    3. N. Andreasen, MD, PhD,
    4. R. Zinkowski, PhD,
    5. K. Ishiguro, PhD,
    6. E. Vanmechelen, PhD,
    7. S. J. Teipel, MD,
    8. C. Graz, MD,
    9. K. Blennow, MD, PhDand
    10. H. Hampel, MD
  1. K. Buerger, MD,
  2. M. Ewers, PhD,
  3. N. Andreasen, MD, PhD,
  4. R. Zinkowski, PhD,
  5. K. Ishiguro, PhD,
  6. E. Vanmechelen, PhD,
  7. S. J. Teipel, MD,
  8. C. Graz, MD,
  9. K. Blennow, MD, PhDand
  10. H. Hampel, MD
  1. From the Dementia Research Section and Memory Clinic (Drs. Buerger, Ewers, Teipel, Graz, and Hampel), Alzheimer Memorial Center, and Geriatric Psychiatry Branch, Department of Psychiatry, Ludwig Maximilian University, Munich, Germany; Karolinska Institutet (Dr. Andreasen), Neurotec, Division of Geriatric Medicine, Huddinge University Hospital, Stockholm, Sweden; Applied NeuroSolutions Inc. (Dr. Zinkowski), Vernon Hills, IL; Mitsubishi Kagaku Institute of Life Sciences (Dr. Ishiguro), Tokyo, Japan; Innogenetics NV (Dr. Vanmechelen), Gent, Belgium; and Department of Clinical Neuroscience (Dr. Blennow), Unit of Neurochemistry, University of Göteborg, Sahlgren’s University Hospital, Mölndal, Sweden.
  1. Address correspondence and reprint requests to Dr. K. Buerger, Department of Psychiatry, Ludwig-Maximilian University, Nussbaumstrasse 7, 80336 Munich, Germany; e-mail:katharina.buerger{at}med.uni-muenchen.de
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