p。L302P溶酶体酶的突变基因SMPD1帕金森病的一个危险因素吗

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.

从遗传研究所(Z.G.-O。,A.B.-S。,M.G.-W。,L.R.,A.O.-U.) and Movement Disorders Unit, Parkinson Center, Department of Neurology (A.M., T.G., N.G.), Tel-Aviv Sourasky Medical Center, Tel Aviv; The Sackler Faculty of Medicine (Z.G.-O., T.G., N.G., A.O.-U.), Tel-Aviv University, Tel Aviv, Israel; The Departments of Genetics and Genomics Sciences (L.J.O., R.K.), Mount Sinai School of Medicine, New York; The Department of Neurology (R.S.-P., D.R., A.D., S.B.B.), Beth Israel Medical Center, New York; and The Departments of Neurology (R.S.-P., S.B.B.) and Genetics (N.S.-A.) and the Department of Obstetrics and Gynecology (S.J.G.) and the Human Genetics Laboratory at Jacobi Medical Center (S.J.G., N.S.-A.), North Bronx Healthcare Network, Albert Einstein College of Medicine, New York, NY.