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March 20, 2018; 90 (12) Editorial

Personalizing acute therapies for ischemic stroke

Thrombolysis or thrombectomy?

Jin-Moo Lee, Tomasz Dziedzic
First published February 14, 2018, DOI: https://doi.org/10.1212/WNL.0000000000005169
Jin-Moo Lee
From the Departments of Neurology, Radiology, and Biomedical Engineering (J.-M.L.), and the Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO; and Department of Neurology (T.D.), Jagiellonian University, Krakow, Poland.
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Tomasz Dziedzic
From the Departments of Neurology, Radiology, and Biomedical Engineering (J.-M.L.), and the Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO; and Department of Neurology (T.D.), Jagiellonian University, Krakow, Poland.
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Citation
Personalizing acute therapies for ischemic stroke
Thrombolysis or thrombectomy?
Jin-Moo Lee, Tomasz Dziedzic
Neurology Mar 2018, 90 (12) 535-536; DOI: 10.1212/WNL.0000000000005169

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The last 2 years has seen unprecedented advances in acute stroke care. In 2015, multiple independent clinical trials demonstrated that endovascular thrombectomy early after acute ischemic stroke (AIS) onset is highly effective for reducing long-term disability.1–5 More recently, the DAWN trial demonstrated the efficacy of thrombectomy in select patients up to 24 hours after stroke onset.6 Critical to the success of these trials has been the use of rapid and robust neuroimaging methods that helped select appropriate patients based on clot location or core/penumbral signatures. Neuroimaging has become the precision medicine equivalent in AIS, personalizing care based on advanced imaging measures.7

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  • Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the editorial.

  • See page 539

  • © 2018 American Academy of Neurology
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Letters: Rapid online correspondence

  • Author response to Dr. Munakomi
    • Jin-Moo Lee, Stroke Neurologist, Washington University School of Medicine
    Submitted March 30, 2018
  • Reader response: Personalizing acute therapies for ischemic stroke
    • Sunil Munakomi, Neurosurgeon, Nobel Teaching Hospital (Biratnagar, Nepal)
    Submitted March 20, 2018
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